Testosterone is the main male sex steroid produced by Leydig cells in the testes, with an average secretion rate of 7 mg/day. Based on calculations from spermatic vein/peripheral vein gradients. Leydig cells can also release intermediate metabolites such as androsterone, androstenedione, 17-OH progesterone, progesterone, and Pregnenolone. Approximately 5% of the T pool is of … Continue reading Don’t Let Hormones Hold You Back: The Importance of Testing Free and Total Testosterone